Friday, October 10, 2014

Effectiveness of Silver in antibiotics

For thousands of years, precious metal have been utilized to fight infections. However, it has been a mystery for sometime on how some, like silver, can disrupt bacteria. According to James Collins, a biomedical engineer at Boston University, silver may help fight against “drug-resistant bacteria such as Stenotrophomonas maltophilia.” Silver as dissolved ions makes the cell membrane more permeable and interferes with the cell’s metabolism. This leads to the overproduction of reactive and toxic oxygen compounds which could possibly make today’s antibiotics more effective.
Silver is shown to be effective on “Gram-negative bacteria’ that can often be impenetrable to antibiotics. The overproduction of oxygen compounds resulting from silver ions increases the bacteria’s membrane permeability which allows antibiotics to enter and shut down their resistance mechanisms. However, the toxicity of silver has to be taken into account before adding it to antibiotics.
I found this article interesting because silver in antibiotics has been controversial in terms of its effectiveness. Many science articles such as WebMD often claim that silver has no known functions in the body nor is it an essential mineral support. Moreover, silver (to be more specific, colloidal silver) products marketed for “medical purposes or promoted for unproven uses are not considered ‘misbranded’ under the law.” It will probably take some more time to diagnose more tests of silver as an agent in antibiotics before it is believable that it does treat infections such as tuberculosis, Lyme disease, pneumonia, and so on.




Submitted by Hanh L. Pham

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